Tuesday, August 23, 2011

Wholesale Clothing, Accessories, Jewelry and Sunglasses Distributor Apparel Candy in New Location Expands Product Lines

Los Angeles based Apparel Candy Inc., a major wholesale apparel distributor has moved to its new location on Grand Ave. The new location offers a bigger and wider office space with more than 20,000 square feet of warehouse space to accommodate their 2011 product line expansion.

Los Angeles, CA, August 24, 2011 - Los Angeles based wholesale clothingwholesale distribution industry particularly in the fashion and accessories segment" according to ApparelCandy.com’s CEO Kam Javidzad. "In an economy where keeping jobs is top priority, food and shelter comes first, clothing and accessories becomes luxury. This makes fashion distribution a lot less marketable and thus becomes one of the toughest and most competitive industries in today’s economy" he continued. distributor Apparel Candy Inc. recently moved to its new location. The new location has a larger and wider office space and a 20,000 square foot warehouse. Despite the slow economy, Apparel Candy’s sales volume has tripled over that of previous years. Apparel Candy has been a breath of fresh air from the number of companies going under year after year since 2008. "Reality is, not everybody makes it in the

However, thanks to the internet, the company has survived the cut and continues to grow. The more than 20,000 square foot warehouse is home to ApparelCandy.com’s new product lines. From selling women’s clothes, the company will now carry wholesale sunglasses, fashion jewelry and accessories to start with on its online store with an ever increasing variety of product lines in the months ahead. The move is predominantly aimed at keeping the customers in one place to shop. While the move is rather risky in today’s economy where inventory could be sitting in warehouse for months if not years, the soft launch proved to be more encouraging than anticipated.

To facilitate the product line expansion, the company secured partnerships with reliable and known brand manufacturers, liquidators, warehouses and importers for a regular supply of fashion sunglasses, wholesale jewelry and accessories allowing Apparel Candy to offer quality, low-cost, name brand or not, the newest, trendiest and hard to find products to its customer base. The expansion is in response to customers’ requests and inquiries to bring these product lines available to its online store. The new development had been shared thru the company’s e-newsletters, blogs, Facebook® and Twitter® accounts and online press releases to the delight of its current customers.

What lies ahead for ApparelCandy.com in the coming months remains to be seen. For now, business is good and the company is dedicated to keeping it that way. To learn more, ApparelCandy.com is open Monday - Friday from 9 AM to 5 PM pacific standard time (PST). Call 1-877-870-8686 or online at http://www.apparelcandy.com.

Contact:
Michelle Williams
Search Marketing Specialist
3022 S. Grand Ave
Los Angeles, CA 90007
(877)-870-8686

Clues to HIV Persistence on ART

Recent research has found that while antiretroviral therapy (ART) is effective at significantly reducing the number of plasma-to-T-cell transmissions of HIV, it's not as effective against T-cell-to-T-cell. The remaining virus hides in infected T-cells, which allows it to easily be passed on to non-infected ones; this, in fact, is one of the reasons why HIV persists through ART.

Toulon, France, August 23, 2011 - HIV has a built-in backup plan when it comes to its survival. While scientific technology has progressed to the point where antiretroviral drugs can effectively kill HIV viruses in the body that are out in the open, HIV persists in places where the drugs can't get to them. These places are called HIV reservoirs, and these reservoirs ensure that small batches of virus remain in the body, ready to replicate when necessary. This is part of what makes HIV a chronic infection—the remaining virus finds ways to remain dormant in the body until activated. Research is now focusing on cracking the case of HIV persistence.

The goal of researchers now is to remove the "chronic" term from the chronic illness that is HIV and come up with a cure for the disease. A better understanding of HIV and how it infects people to begin with might be the key to discovering ways to enter the reservoirs within the body and eliminate the virus. As we already know, HIV infects cells in two ways: through blood plasma contact with T-cells, and from infected T-cells to non-infected T-cells. Antiretroviral drugs, while effective, don't remove the entire virus quantity, and all it takes is for one HIV virus to remain behind for the replication to continue.

Recent research has found that while antiretroviral therapy (ART) is effective at significantly reducing the number of plasma-to-T-cell transmissions of HIV, it's not as effective against T-cell-to-T-cell. The remaining virus hides in infected T-cells, which allows it to easily be passed on to non-infected ones; this, in fact, is one of the reasons why HIV persists through ART. To use a football analogy, ART is able to intercept passes through the air (plasma) from one cell to another, but it can't stop direct handoffs. A strategy is needed to defend against each separately, because the same defense can't be used against both.

Even with antiretroviral drugs present, infected T-cells can still infect other T-cells in close quarters instead of through the bloodstream; this often happens in the lymph nodes. Therefore, in order to find an actual cure for HIV, researchers need to find a way to deal with HIV reservoirs filled with both latent HIV virus and active virus that is transmitted from cell-to-cell. The clues to HIV persistence are clear, but this is one of those situations where the answer seems obvious but the path toward deriving the answer is extremely difficult.

Contact:
Alain Lafeuillade
AVPS
1208 avenue Colonel Picot
Toulon 83100 France
33-4-94616340