Oxford Expression Technologies, the award-winning specialist provider of baculovirus-based protein expression solutions, has launched baculoFECTIN.
Oxford, UK, April 04, 2011 - Oxford Expression Technologies, the award-winning specialist provider of baculovirus-based protein expression solutions, has launched baculoFECTIN. This new non-toxic transfection reagent has been optimized for use in insect cells and proven to produce greater levels of transfection - leading to high level protein expression.
The transfection spectrum comprises various established cell lines and primary cells. baculoFECTIN consists of two components, a positively charged polymer with DNA-binding capacity that is embedded into a novel porous nanoparticle. The complete nanoparticle complex protects the bound DNA from degradation by nucleases. Only the DNA nanoparticle complex with its unique size can be preferentially taken up by the cells. Within the cells, the released DNA-nanoparticle complexes are protected against DNA degradation.
"The main benefits of baculoFECTIN compared with lipid-based products are that it has a quick, effective and easy protocol, from co-transfection to high titre seed stock; it is non-toxic so cell health and viability is maintained; and the nanoparticle/polymer duplex optimizes entry into cells and stabilizes the DNA within transfected insect cells," said Richard Broadhead, sales and marketing manager at Oxford Expression Tehnologies. "Stable for up to a year, baculoFECTIN is the perfect companion to our leading baculovirus expression system flashBAC. It is ideal for high-throughput transfection experiments."
For more information, visit: www.oxfordexpression.com
About Oxford Expression Technologies:
Oxford Expression Technologies is a biotechnology company and centre of excellence for baculovirus protein expression. Specializing in the use of the baculovirus expression vector system, a eukaryotic expression system that can express a large variety of recombinant proteins, Oxford Expression Technologies provides protein expression products, services and consultancy to many global pharmaceutical companies. The Company’s proprietary flashBAC technology enables large amounts of a given protein to be produced in culture. Its internationally renowned expertise and products enable proteins to be produced faster, more easily and cost-effectively using automated and high-throughput methods compared with other baculovirus expression systems. This contributes to the development of new drugs and research targeted towards understanding how proteins work in health and disease.
The company was founded in 2007 as a result of collaboration between Oxford Brookes University and the Natural Environment Research Council to provide researchers with custom proteins for research purposes.
For Further information or an illustrative image: Media contact - Mathew Taylor, Director, Algorythm Solutions Ltd, mobile: +44 (0)773 403 2112, email: mtaylor@algorythmsolutions.com, website: www.algorythmsolutions.com
Contact:
Mathew Taylor
Director
Algorythm Solutions Ltd
10 Torkington St
Stamford, Lincolnshire PE9 2UY
+44 (0)773 403 2112
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